Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice

Sirt1 plays an important role in regulating glucose and lipid metabolism in obese animal models. Impaired adipose tissue angiogenesis in the obese state decreases adipogenesis and thereby contributes to glucose intolerance and lipid metabolism. However, the mechanism by which Sirt1 activation affect...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Nawaz, Allah, Mehmood, Arshad, Kanatani, Yukiko, Kado, Tomonobu, Igarashi, Yoshiko, Takikawa, Akiko, Yamamoto, Seiji, Okabe, Keisuke, Nakagawa, Takashi, Yagi, Kunimasa, Fujisaka, Shiho, Tobe, Kazuyuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063897/
https://ncbi.nlm.nih.gov/pubmed/30054532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29773-0
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