Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity

Obesity and insulin resistance are associated with dysbiosis of the gut microbiota and impaired intestinal barrier function. Herein, we report that Bofutsushosan (BFT), a Japanese herbal medicine, Kampo, which has been clinically used for constipation in Asian countries, ameliorates glucose metaboli...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fujisaka, Shiho, Usui, Isao, Nawaz, Allah, Igarashi, Yoshiko, Okabe, Keisuke, Furusawa, Yukihiro, Watanabe, Shiro, Yamamoto, Seiji, Sasahara, Masakiyo, Watanabe, Yoshiyuki, Nagai, Yoshinori, Yagi, Kunimasa, Nakagawa, Takashi, Tobe, Kazuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099031/
https://ncbi.nlm.nih.gov/pubmed/32218475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62506-w
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