Microfluidic Tumor-on-a-Chip Model to Study Tumor Metabolic Vulnerability

Tumor-specific metabolic adaptations offer an interesting therapeutic opportunity to selectively destroy cancer cells. However, solid tumors also present gradients of nutrients and waste products across the tumor mass, forcing tumor cells to adapt their metabolism depending on nutrient availability...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ayuso, Jose M, Rehman, Shujah, Farooqui, Mehtab, Virumbrales-Muñoz, María, Setaluri, Vijayasaradhi, Skala, Melissa C, Beebe, David J
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730115/
https://ncbi.nlm.nih.gov/pubmed/33260673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239075
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