Microfluidic model with air-walls reveals fibroblasts and keratinocytes modulate melanoma cell phenotype, migration, and metabolism

Melanoma evolution is a complex process. The role epidermal keratinocytes and dermal fibroblasts play in this process and the mechanisms involved in tumor-stroma interactions remain poorly understood. Here, we used a microfluidic platform to evaluate the cross-talk between human primary melanoma cel...

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Bibliographic Details
Published in:Lab Chip
Main Authors: Ayuso, Jose M, Sadangi, Shreyans, Lares, Marcos, Rehman, Shujah, Humayun, Mouhita, Denecke, Kathryn M, Skala, Melissa C, Beebe, David J, Setaluri, Vijayasaradhi
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990711/
https://ncbi.nlm.nih.gov/pubmed/33533390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0lc00988a
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