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Tumor-on-a-chip: a microfluidic model to study cell response to environmental gradients.
Limited blood supply and rapid tumor metabolism within solid tumors leads to nutrient starvation, waste product accumulation and the generation of pH gradients across the tumor mass. These environmental conditions modify multiple cellular functions, including metabolism, proliferation, and drug resp...
Guardado en:
| Publicado en: | Lab Chip |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6785375/ https://ncbi.nlm.nih.gov/pubmed/31506657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9lc00270g |
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