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Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model

Immunotherapies against solid tumors face additional challenges compared with hematological cancers. In solid tumors, immune cells and antibodies need to extravasate from vasculature, find the tumor, and migrate through a dense mass of cells. These multiple steps pose significant obstacles for solid...

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Bibliografiska uppgifter
I publikationen:Oncoimmunology
Huvudupphovsmän: Ayuso, Jose M., Truttschel, Regan, Gong, Max M., Humayun, Mouhita, Virumbrales-Munoz, Maria, Vitek, Ross, Felder, Mildred, Gillies, Stephen D., Sondel, Paul, Wisinski, Kari B., Patankar, Manish, Beebe, David J., Skala, Melissa C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2018
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350694/
https://ncbi.nlm.nih.gov/pubmed/30723584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1553477
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