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Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA

INTRODUCTION: Increased activity of matrix metalloproteases (MMPs) is associated with reduced survival in several cancer subtypes. Aiming to produce an MMP tumour cell-selective cytotoxin, we genetically modified both components of the AB–type lethal toxin from Bacillus anthracis. Component A, Prote...

詳細記述

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書誌詳細
出版年:Nucl Med Biol
主要な著者: Xavier, Mary-Ann Elvina, Liu, Shihui, Leppla, Stephen H., Cornelissen, Bart
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730038/
https://ncbi.nlm.nih.gov/pubmed/31330412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2019.07.007
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