Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens

Technologies to reprogram cell-type specification have revolutionized the fields of regenerative medicine and disease modeling. Currently, the selection of fate-determining factors for cell reprogramming applications is typically a laborious and low-throughput process. Therefore, we use high-through...

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Publicado no:Cell Rep
Main Authors: Black, Joshua B., McCutcheon, Sean R., Dube, Shataakshi, Barrera, Alejandro, Klann, Tyler S., Rice, Grayson A., Adkar, Shaunak S., Soderling, Scott H., Reddy, Timothy E., Gersbach, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730023/
https://ncbi.nlm.nih.gov/pubmed/33264623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108460
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