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Wrangling Shape-Shifting Morpheeins to Tackle Disease and Approach Drug Discovery
Homo-multimeric proteins that can come apart, change shape, and reassemble differently with functional consequences have been called morpheeins and/or transformers; these provide a largely unexplored context for understanding disease and developing allosteric therapeutics. This article describes suc...
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| 發表在: | Front Mol Biosci |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7729013/ https://ncbi.nlm.nih.gov/pubmed/33330623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.582966 |
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