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MORPHEEINS – A NEW PATHWAY FOR ALLOSTERIC DRUG DISCOVERY

The morpheein model of allosteric regulation can be applied as a novel approach to the discovery of small molecule allosteric modulators of protein function. Morpheeins are homo-oligomeric proteins where, under physiological conditions, the oligomer can dissociate, the dissociated units can change c...

Täydet tiedot

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Bibliografiset tiedot
Päätekijä: JAFFE, EILEEN K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107518/
https://ncbi.nlm.nih.gov/pubmed/21643557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2210289201001010001
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