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MORPHEEINS – A NEW PATHWAY FOR ALLOSTERIC DRUG DISCOVERY
The morpheein model of allosteric regulation can be applied as a novel approach to the discovery of small molecule allosteric modulators of protein function. Morpheeins are homo-oligomeric proteins where, under physiological conditions, the oligomer can dissociate, the dissociated units can change c...
Tallennettuna:
| Päätekijä: | |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107518/ https://ncbi.nlm.nih.gov/pubmed/21643557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2210289201001010001 |
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