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Inference of mutability landscapes of tumors from single cell sequencing data
One of the hallmarks of cancer is the extremely high mutability and genetic instability of tumor cells. Inherent heterogeneity of intra-tumor populations manifests itself in high variability of clone instability rates. Analogously to fitness landscapes, the instability rates of clonal populations fo...
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| Publicat a: | PLoS Comput Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7728263/ https://ncbi.nlm.nih.gov/pubmed/33253159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008454 |
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