Inference of genetic relatedness between viral quasispecies from sequencing data

Abstract Background RNA viruses such as HCV and HIV mutate at extremely high rates, and as a result, they exist in infected hosts as populations of genetically related variants. Recent advances in sequencing technologies make possible to identify such populations at great depth. In particular, these...

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Detalhes bibliográficos
Main Authors: Olga Glebova, Sergey Knyazev, Andrew Melnyk, Alexander Artyomenko, Yury Khudyakov, Alex Zelikovsky, Pavel Skums
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-12-01
Colecção:BMC Genomics
Assuntos:
Genetic relatedness
Transmission networks
Outbreaks investigations
Simulation
Clustering
Acesso em linha:http://link.springer.com/article/10.1186/s12864-017-4274-5
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