Reconstruction of viral population structure from next-generation sequencing data using multicommodity flows

BACKGROUND: Highly mutable RNA viruses exist in infected hosts as heterogeneous populations of genetically close variants known as quasispecies. Next-generation sequencing (NGS) allows for analysing a large number of viral sequences from infected patients, presenting a novel opportunity for studying...

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Autors principals: Skums, Pavel, Mancuso, Nicholas, Artyomenko, Alexander, Tork, Bassam, Mandoiu, Ion, Khudyakov, Yury, Zelikovsky, Alex
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698000/
https://ncbi.nlm.nih.gov/pubmed/23902469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S9-S2
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