Efficient error correction for next-generation sequencing of viral amplicons

BACKGROUND: Next-generation sequencing allows the analysis of an unprecedented number of viral sequence variants from infected patients, presenting a novel opportunity for understanding virus evolution, drug resistance and immune escape. However, sequencing in bulk is error prone. Thus, the generate...

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Bibliografiske detaljer
Main Authors: Skums, Pavel, Dimitrova, Zoya, Campo, David S, Vaughan, Gilberto, Rossi, Livia, Forbi, Joseph C, Yokosawa, Jonny, Zelikovsky, Alex, Khudyakov, Yury
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Proceedings
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382444/
https://ncbi.nlm.nih.gov/pubmed/22759430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S10-S6
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