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Efficient error correction for next-generation sequencing of viral amplicons
BACKGROUND: Next-generation sequencing allows the analysis of an unprecedented number of viral sequence variants from infected patients, presenting a novel opportunity for understanding virus evolution, drug resistance and immune escape. However, sequencing in bulk is error prone. Thus, the generate...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382444/ https://ncbi.nlm.nih.gov/pubmed/22759430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S10-S6 |
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