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Inferring viral quasispecies spectra from 454 pyrosequencing reads

BACKGROUND: RNA viruses infecting a host usually exist as a set of closely related sequences, referred to as quasispecies. The genomic diversity of viral quasispecies is a subject of great interest, particularly for chronic infections, since it can lead to resistance to existing therapies. High-thro...

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Detalhes bibliográficos
Main Authors: Astrovskaya, Irina, Tork, Bassam, Mangul, Serghei, Westbrooks, Kelly, Măndoiu, Ion, Balfe, Peter, Zelikovsky, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194189/
https://ncbi.nlm.nih.gov/pubmed/21989211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S6-S1
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