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A comparison of AAV-vector production methods for gene therapy and preclinical assessment

Adeno Associated Virus (AAV)-mediated gene expression in the brain is widely applied in the preclinical setting to investigate the therapeutic potential of specific molecular targets, characterize various cellular functions, and model central nervous system (CNS) diseases. In therapeutic application...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Davidsson, Marcus, Negrini, Matilde, Hauser, Swantje, Svanbergsson, Alexander, Lockowandt, Marcus, Tomasello, Giuseppe, Manfredsson, Fredric P., Heuer, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726153/
https://ncbi.nlm.nih.gov/pubmed/33299011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78521-w
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