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A comparison of AAV-vector production methods for gene therapy and preclinical assessment

Adeno Associated Virus (AAV)-mediated gene expression in the brain is widely applied in the preclinical setting to investigate the therapeutic potential of specific molecular targets, characterize various cellular functions, and model central nervous system (CNS) diseases. In therapeutic application...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Davidsson, Marcus, Negrini, Matilde, Hauser, Swantje, Svanbergsson, Alexander, Lockowandt, Marcus, Tomasello, Giuseppe, Manfredsson, Fredric P., Heuer, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726153/
https://ncbi.nlm.nih.gov/pubmed/33299011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78521-w
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