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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

DNA crosslinking agents are widely used in cancer chemotherapy; however, responses of normal tissues to these agents have not been widely investigated. We reveal in mouse interfollicular epidermis, mammary gland, and hair follicle epithelia that genotoxicity does not promote apoptosis but paradoxica...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Dev Cell
Egile Nagusiak: Seldin, Lindsey, Macara, Ian G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725994/
https://ncbi.nlm.nih.gov/pubmed/33058780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.09.021
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