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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation
DNA crosslinking agents are widely used in cancer chemotherapy; however, responses of normal tissues to these agents have not been widely investigated. We reveal in mouse interfollicular epidermis, mammary gland, and hair follicle epithelia that genotoxicity does not promote apoptosis but paradoxica...
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| Veröffentlicht in: | Dev Cell |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7725994/ https://ncbi.nlm.nih.gov/pubmed/33058780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.09.021 |
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