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Improvement of muscular atrophy by AAV–SaCas9-mediated myostatin gene editing in aged mice
Muscle mass and area usually decrease with age, and this phenomenon is known as sarcopenia. This age-related atrophy correlates with insufficient levels of muscle cells differentiate and proliferate regulated by the TGF-β signaling pathway and the expression of E3s ubiquitin-protein ligase by the ag...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cancer Gene Ther |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group US
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7725670/ https://ncbi.nlm.nih.gov/pubmed/32398787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41417-020-0178-7 |
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