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Manipulating the Tumor Microenvironment in Tumor Organoids Induces Phenotypic Changes and Chemoresistance

Tumors comprised a tightly surrounded tumor microenvironment, made up of non-cellular extracellular matrix (ECM) and stromal cells. Although treatment response is often attributed to tumor heterogeneity, progression and malignancy are profoundly influenced by tumor cell interactions with the surroun...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:iScience
Main Authors: Dominijanni, Anthony, Devarasetty, Mahesh, Soker, Shay
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724203/
https://ncbi.nlm.nih.gov/pubmed/33319176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101851
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