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Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo

The tumor microenvironment (TME) plays a significant role in cancer progression and thus modeling it will advance our understanding of cancer growth dynamics and response to therapies. Most in vitro models are not exposed to intact body physiology, and at the same time, fail to recapitulate the exte...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Devarasetty, Mahesh, Dominijanni, Anthony, Herberg, Samuel, Shelkey, Ethan, Skardal, Aleksander, Soker, Shay
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300090/
https://ncbi.nlm.nih.gov/pubmed/32555362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66785-1
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