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Bioengineered Submucosal Organoids for In Vitro Modeling of Colorectal Cancer

The physical nature of the tumor microenvironment significantly impacts tumor growth, invasion, and response to drugs. Most in vitro tumor models are designed to study the effects of extracellular matrix (ECM) stiffness on tumor cells, while not addressing the effects of ECM's specific topograp...

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Detalhes bibliográficos
Publicado no:Tissue Eng Part A
Main Authors: Devarasetty, Mahesh, Skardal, Aleksander, Cowdrick, Kyle, Marini, Frank, Soker, Shay
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653148/
https://ncbi.nlm.nih.gov/pubmed/28922975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2017.0397
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