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Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro

Current in vitro models for tumor growth and metastasis are poor facsimiles of in vivo cancer physiology and thus, are not optimal for anti-cancer drug development. Three dimensional (3D) tissue organoid systems, which utilize human cells in a tailored microenvironment, have the potential to recapit...

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Detalhes bibliográficos
Publicado no:Ann Biomed Eng
Main Authors: Skardal, Aleksander, Devarasetty, Mahesh, Rodman, Christopher, Atala, Anthony, Soker, Shay
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573342/
https://ncbi.nlm.nih.gov/pubmed/25777294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-015-1298-3
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