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Bioengineered Submucosal Organoids for In Vitro Modeling of Colorectal Cancer

The physical nature of the tumor microenvironment significantly impacts tumor growth, invasion, and response to drugs. Most in vitro tumor models are designed to study the effects of extracellular matrix (ECM) stiffness on tumor cells, while not addressing the effects of ECM's specific topograp...

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Bibliografiska uppgifter
I publikationen:Tissue Eng Part A
Huvudupphovsmän: Devarasetty, Mahesh, Skardal, Aleksander, Cowdrick, Kyle, Marini, Frank, Soker, Shay
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653148/
https://ncbi.nlm.nih.gov/pubmed/28922975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2017.0397
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