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New Perspectives for Resistance to PARP Inhibitors in Triple-Negative Breast Cancer
Poly (ADP-ribose) polymerase (PARP) inhibitors are a therapeutic milestone exerting a synthetic lethal effect in the treatment of cancer involving BRCA1/2 mutation. Theoretically, PARP inhibitors (PARPi) eliminate tumor cells by disrupting DNA damage repair through either PARylation or the homologou...
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| Publicado en: | Front Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7724080/ https://ncbi.nlm.nih.gov/pubmed/33324554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.578095 |
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