Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer

The limited treatment options and therapeutic failure due to acquired resistance for patients with triple-negative breast cancer (TNBC) represent a significant challenge. Inhibitors against poly (ADP-ribose) polymerase (PARP), olaparib and talazoparib, were recently approved for the treatment of met...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Chu, Yu-Yi, Yam, Clinton, Chen, Mei-Kuang, Chan, Li-Chuan, Xiao, Min, Wei, Yong-Kun, Yamaguchi, Hirohito, Lee, Pei-Chih, Han, Ye, Nie, Lei, Sun, Xian, Moulder, Stacy L, Hess, Kenneth R, Wang, Bin, Hsu, Jennifer L, Hortobagyi, Gabriel N, Litton, Jennifer, Chang, Jeffrey T, Hung, Mien-Chie
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061756/
https://ncbi.nlm.nih.gov/pubmed/32195033
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