Expression of Oncolytic Adenovirus-Encoded RNAi Molecules Is Most Effective in a pri-miRNA Precursor Format

Oncolytic adenoviruses are being developed as new anti-cancer agents. Their efficacy can be improved by incorporating RNA interference (RNAi) molecules. RNAi molecules can be expressed in various precursor formats. The aim of this study was to determine the most effective format. To this end, we con...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Oncolytics
Päätekijät: Brachtlova, Tereza, van Ginkel, Jan-Willem, Luinenburg, Mark J., de Menezes, Renée X., Koppers-Lalic, Danijela, Pegtel, D. Michiel, Dong, Wenliang, de Gruijl, Tanja D., van Beusechem, Victor W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2020
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723779/
https://ncbi.nlm.nih.gov/pubmed/33335978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.10.012
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