Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

Hyperlipidemia is a well-established risk factor for cardiovascular diseases. Millions of people worldwide display mildly elevated levels of plasma lipids and cholesterol linked to diet and life-style. While the prothrombotic risk of severe hyperlipidemia has been established, the effects of moderat...

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發表在:Sci Rep
Main Authors: van Geffen, Johanna P., Swieringa, Frauke, van Kuijk, Kim, Tullemans, Bibian M. E., Solari, Fiorella A., Peng, Bing, Clemetson, Kenneth J., Farndale, Richard W., Dubois, Ludwig J., Sickmann, Albert, Zahedi, René P., Ahrends, Robert, Biessen, Erik A. L., Sluimer, Judith C., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722935/
https://ncbi.nlm.nih.gov/pubmed/33293576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78522-9
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