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Inhibitory designer receptors aggravate memory loss in a mouse model of down syndrome
The pontine nucleus locus coeruleus (LC) is the primary source of noradrenergic (NE) projections to the brain and is important for working memory, attention, and cognitive flexibility. Individuals with Down syndrome (DS) develop Alzheimer's disease (AD) with high penetrance and often exhibit wo...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7722242/ https://ncbi.nlm.nih.gov/pubmed/31678403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104616 |
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