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Inhibitory designer receptors aggravate memory loss in a mouse model of down syndrome

The pontine nucleus locus coeruleus (LC) is the primary source of noradrenergic (NE) projections to the brain and is important for working memory, attention, and cognitive flexibility. Individuals with Down syndrome (DS) develop Alzheimer's disease (AD) with high penetrance and often exhibit wo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neurobiol Dis
मुख्य लेखकों: Hamlett, Eric D., Ledreux, Aurélie, Gilmore, Anah, Vazey, Elena M., Aston-Jones, Gary, Boger, Heather A., Paredes, Daniel, Granholm, Ann-Charlotte E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722242/
https://ncbi.nlm.nih.gov/pubmed/31678403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104616
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