Designer Receptors Enhance Memory in a Mouse Model of Down Syndrome

Designer receptors exclusively activated by designer drugs (DREADDs) are novel and powerful tools to investigate discrete neuronal populations in the brain. We have used DREADDs to stimulate degenerating neurons in a Down syndrome (DS) model, Ts65Dn mice. Individuals with DS develop Alzheimer's...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Fortress, Ashley M., Hamlett, Eric D., Vazey, Elena M., Aston-Jones, Gary, Cass, Wayne A., Boger, Heather A., Granholm, Ann-Charlotte E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2015
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308587/
https://ncbi.nlm.nih.gov/pubmed/25632113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2658-14.2015
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