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Deficiency in Acyl-CoA:Wax Alcohol Acyltransferase 2 causes evaporative dry eye disease by abolishing biosynthesis of wax esters
Lipids secreted by the meibomian glands (MGs) of the eyelids are essential to the protection of the eye’s surface. An altered meibum composition represents the primary cause of evaporative dry eye disease (DED). Despite the critical importance of the meibum, its biosynthetic pathways and the roles o...
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| Veröffentlicht in: | FASEB J |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7722226/ https://ncbi.nlm.nih.gov/pubmed/32851726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001191R |
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