Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1

Cellular retinol-binding proteins (CRBPs) facilitate the uptake and intracellular transport of vitamin A. They integrate retinoid metabolism, playing an important role in regulating the synthesis of bioactive vitamin A metabolites. Thus, CRBPs constitute potential pharmacological targets to modulate...

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Gepubliceerd in:ACS Chem Biol
Hoofdauteurs: Silvaroli, Josie A., Widjaja-Adhi, Made Airanthi K., Trischman, Thomas, Chelstowska, Sylwia, Horwitz, Samantha, Banerjee, Surajit, Kiser, Philip D., Blaner, William S., Golczak, Marcin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420351/
https://ncbi.nlm.nih.gov/pubmed/30721022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b01070
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