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In vivo enrichment of genetically manipulated platelets for murine hemophilia B gene therapy
Our previous studies have demonstrated that platelet-targeted FIX gene therapy can introduce sustained platelet-FIX expression in hemophilia B (FIX(null)) mice. In this study, we aimed to enhance platelet-FIX expression in FIX(null) mice with MGMT-mediated in vivo drug selection of transduced cells...
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| Udgivet i: | J Cell Physiol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7722216/ https://ncbi.nlm.nih.gov/pubmed/32510630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29861 |
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