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The Unfolded Protein Response in Leukemia: from Basic Understanding to Therapeutic Opportunities

Understanding genetic and epigenetic changes that underlie abnormal proliferation of hematopoietic stem and progenitor cells is critical for development of new approaches to monitor and treat leukemia. The unfolded protein response (UPR) is a conserved adaptive signaling pathway that governs protein...

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Publicado en:Trends Cancer
Autores principales: Khateb, Ali, Ronai, Ze’ev A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721105/
https://ncbi.nlm.nih.gov/pubmed/32540455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.05.012
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