The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities

Recent studies indicate the importance of the ubiquitin ligase Siah2 in control of more aggressive prostate tumors – namely, neuroendocrine (NE) prostate tumors and prostate adenocarcinoma (PCa) harboring neuroendocrine lesions. Siah2-dependent expression and activity of HIF-1α regulate its availabi...

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Bibliografske podrobnosti
Main Authors: Qi, Jianfei, Pellecchia, Maurizio, Ronai, Ze'ev A.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2010
Teme:
Research Perspectives
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964873/
https://ncbi.nlm.nih.gov/pubmed/21037926
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