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The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias
The unfolded protein response (UPR) is an evolutionarily conserved adaptive response triggered by the stress of the endoplasmic reticulum (ER) due, among other causes, to altered cell protein homeostasis (proteostasis). UPR is mediated by three main sensors, protein kinase RNA-like endoplasmic retic...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7072709/ https://ncbi.nlm.nih.gov/pubmed/32024211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020333 |
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