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JAMP Optimizes ERAD to Protect Cells from Unfolded Proteins

Clearance of misfolded proteins from the ER is central for maintenance of cellular homeostasis. This process requires coordinated recognition, ER-cytosol translocation, and finally ubiquitination-dependent proteasomal degradation. Here, we identify an ER resident seven-transmembrane protein (JAMP) t...

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Detalhes bibliográficos
Main Authors: Tcherpakov, Marianna, Broday, Limor, Delaunay, Agnes, Kadoya, Takayuki, Khurana, Ashwani, Erdjument-Bromage, Hediye, Tempst, Paul, Qiu, Xiao-Bo, DeMartino, George N., Ronai, Ze'ev
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575167/
https://ncbi.nlm.nih.gov/pubmed/18784250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0839
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