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JAMP Optimizes ERAD to Protect Cells from Unfolded Proteins
Clearance of misfolded proteins from the ER is central for maintenance of cellular homeostasis. This process requires coordinated recognition, ER-cytosol translocation, and finally ubiquitination-dependent proteasomal degradation. Here, we identify an ER resident seven-transmembrane protein (JAMP) t...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575167/ https://ncbi.nlm.nih.gov/pubmed/18784250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0839 |
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