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Weekly injection of IL-2 using an injectable hydrogel reduces autoimmune diabetes incidence in NOD mice
AIMS/HYPOTHESIS: IL-2 injections are a promising therapy for autoimmune type 1 diabetes but the short half-life of this cytokine in vivo limits effective tissue exposure and necessitates frequent injections. Here we have investigated whether an injectable hydrogel could be used to promote prolonged...
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| Publicado no: | Diabetologia |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720893/ https://ncbi.nlm.nih.gov/pubmed/33125521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-020-05314-1 |
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