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Structural analysis of the polo-box domain of human Polo-like kinase 2
Polo-like kinases (Plks) are the key regulators of cell cycle progression, the members of which share a kinase domain and a polo-box domain (PBD) that serves as a protein-binding module. While Plk1 is a promising target for antitumor therapy, Plk2 is regarded as a tumor suppressor even though the tw...
Uloženo v:
| Vydáno v: | Proteins |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720676/ https://ncbi.nlm.nih.gov/pubmed/25846005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24804 |
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