Polo-Box Domain: a versatile mediator of polo-like kinase function

Members of the polo subfamily of protein kinases have emerged as important regulators in diverse aspects of the cell cycle and cell proliferation. A large body of evidence suggests that a highly conserved polo-box domain (PBD) present in the C-terminal non-catalytic region of polo kinases play a piv...

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Main Authors: Park, Jung-Eun, Soung, Nak-Kyun, Yoshikazu, Johmura, Kang, Young H., Liao, Chenzhong, Lee, Kyung H., Park, Chi Hoon, Nicklaus, Marc C., Lee, Kyung S.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877763/
https://ncbi.nlm.nih.gov/pubmed/20148280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0279-9
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