Llwytho...

The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex

Human polo-like kinase Plk1 localizes to the centrosomes, kinetochores and central spindle structures during mitosis. It plays an essential role in promoting mitosis and cytokinesis through phosphorylation of a number of different substrates. Kinase activity is regulated by a conserved C-terminal do...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cheng, Kin-Yip, Lowe, Edward D., Sinclair, John, Nigg, Erich A., Johnson, Louise N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC275415/
https://ncbi.nlm.nih.gov/pubmed/14592974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg558
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