An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling

Agonist binding promotes activation of G protein-coupled receptors (GPCRs) and association of active receptors with G protein heterotrimers. The resulting active-state ternary complex is the basis for conventional stimulus-response coupling. Although GPCRs can also associate with G proteins before a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jang, Wonjo, Adams, C. Elizabeth, Liu, Heng, Zhang, Cheng, Levy, Finn Olav, Andressen, Kjetil Wessel, Lambert, Nevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720138/
https://ncbi.nlm.nih.gov/pubmed/33199589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010801117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados