טוען...
An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling
Agonist binding promotes activation of G protein-coupled receptors (GPCRs) and association of active receptors with G protein heterotrimers. The resulting active-state ternary complex is the basis for conventional stimulus-response coupling. Although GPCRs can also associate with G proteins before a...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720138/ https://ncbi.nlm.nih.gov/pubmed/33199589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010801117 |
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