Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at an advanced stage, which limits surgical options and portends a dismal prognosis. Current oncologic PDAC therapies confer marginal benefit and, thus, a significant unmet clinical need exists for new therapeutic strategies. To identify...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Grbovic-Huezo, Olivera, Pitter, Kenneth L., Lecomte, Nicolas, Saglimbeni, Joseph, Askan, Gokce, Holm, Matilda, Melchor, Jerry P., Chandwani, Rohit, Joshi, Suhasini, Haglund, Caj, Iacobuzio-Donahue, Christine A., Chiosis, Gabriela, Tammela, Tuomas, Leach, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720119/
https://ncbi.nlm.nih.gov/pubmed/33199632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920240117
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