PanIN neuroendocrine cells promote tumorigenesis via neuronal crosstalk

Nerves are a notable feature of the tumor microenvironment in some epithelial tumors, but their role in the malignant progression of pancreatic ductal adenocarcinoma (PDAC) is uncertain. Here we identify dense innervation in the microenvironment of precancerous pancreatic lesions, known as pancreati...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Sinha, Smrita, Fu, Ya-Yuan, Grimont, Adrien, Ketcham, Maren, Lafaro, Kelly, Saglimbeni, Joseph A., Askan, Gokce, Bailey, Jennifer M., Melchor, Jerry P., Zhong, Yi, Joo, Min Geol, Grbovic-Huezo, Olivera, Yang, In-Hong, Basturk, Olca, Baker, Lindsey, Park, Young, Kurtz, Robert C., Tuveson, David, Leach, Steven D., Pasricha, Pankaj J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471615/
https://ncbi.nlm.nih.gov/pubmed/28386018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0899-T
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