PanIN neuroendocrine cells promote tumorigenesis via neuronal crosstalk

Nerves are a notable feature of the tumor microenvironment in some epithelial tumors, but their role in the malignant progression of pancreatic ductal adenocarcinoma (PDAC) is uncertain. Here we identify dense innervation in the microenvironment of precancerous pancreatic lesions, known as pancreati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Sinha, Smrita, Fu, Ya-Yuan, Grimont, Adrien, Ketcham, Maren, Lafaro, Kelly, Saglimbeni, Joseph A., Askan, Gokce, Bailey, Jennifer M., Melchor, Jerry P., Zhong, Yi, Joo, Min Geol, Grbovic-Huezo, Olivera, Yang, In-Hong, Basturk, Olca, Baker, Lindsey, Park, Young, Kurtz, Robert C., Tuveson, David, Leach, Steven D., Pasricha, Pankaj J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471615/
https://ncbi.nlm.nih.gov/pubmed/28386018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0899-T
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