Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease

BACKGROUND: Among different types of sphingolipids produced by human cells, the possible engagement of ceramide species in the pathogenesis of Alzheimer’s disease (AD) has attracted recent attention. While ceramides are primarily generated by de novo synthesis in mammalian cells, only a limited numb...

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Vydáno v:Front Immunol
Hlavní autoři: Yamada, Chiaki, Akkaoui, Juliet, Ho, Anny, Duarte, Carolina, Deth, Richard, Kawai, Toshihisa, Nichols, Frank, Lakshmana, Madepalli K., Movila, Alexandru
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719741/
https://ncbi.nlm.nih.gov/pubmed/33329577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591571
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