Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease

BACKGROUND: Among different types of sphingolipids produced by human cells, the possible engagement of ceramide species in the pathogenesis of Alzheimer’s disease (AD) has attracted recent attention. While ceramides are primarily generated by de novo synthesis in mammalian cells, only a limited numb...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yamada, Chiaki, Akkaoui, Juliet, Ho, Anny, Duarte, Carolina, Deth, Richard, Kawai, Toshihisa, Nichols, Frank, Lakshmana, Madepalli K., Movila, Alexandru
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719741/
https://ncbi.nlm.nih.gov/pubmed/33329577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591571
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