Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease

BACKGROUND: Among different types of sphingolipids produced by human cells, the possible engagement of ceramide species in the pathogenesis of Alzheimer’s disease (AD) has attracted recent attention. While ceramides are primarily generated by de novo synthesis in mammalian cells, only a limited numb...

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Опубликовано в: :Front Immunol
Главные авторы: Yamada, Chiaki, Akkaoui, Juliet, Ho, Anny, Duarte, Carolina, Deth, Richard, Kawai, Toshihisa, Nichols, Frank, Lakshmana, Madepalli K., Movila, Alexandru
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719741/
https://ncbi.nlm.nih.gov/pubmed/33329577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591571
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