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Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease

BACKGROUND: Among different types of sphingolipids produced by human cells, the possible engagement of ceramide species in the pathogenesis of Alzheimer’s disease (AD) has attracted recent attention. While ceramides are primarily generated by de novo synthesis in mammalian cells, only a limited numb...

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Pubblicato in:Front Immunol
Autori principali: Yamada, Chiaki, Akkaoui, Juliet, Ho, Anny, Duarte, Carolina, Deth, Richard, Kawai, Toshihisa, Nichols, Frank, Lakshmana, Madepalli K., Movila, Alexandru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719741/
https://ncbi.nlm.nih.gov/pubmed/33329577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591571
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