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Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy

A number of poly(ADP-ribose) polymerase (PARP) inhibitors have been recently approved for clinical use in BRCA mutated and other cancers. However, off-target toxicity of PARP inhibitors and the emergence of drug resistance following prolonged administration of these inhibitors indicate the need for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Chem
Hauptverfasser: Singh, Bijay, Yang, Shicheng, Krishna, Apurva, Sridhar, Srinivas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719718/
https://ncbi.nlm.nih.gov/pubmed/33330383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.594619
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