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L-citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs
BACKGROUND: Dysregulated nitric oxide (NO) signaling contributes to chronic hypoxia (CH)-induced pulmonary hypertension (PH). NO signaling is improved and pulmonary vascular resistance (PVR) is reduced in CH piglets treated with the L-arginine-NO precursor, L-citrulline. We hypothesized that L-citru...
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| Publicado no: | Pediatr Pulmonol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7719608/ https://ncbi.nlm.nih.gov/pubmed/32662946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ppul.24960 |
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